Forty nine people were injured and one was killed in a late winter F4 tornado that moved through Tuscaloosa County, Alabama on Sunday February 23, 1975.  The tornado touched down around 12:35 in the afternoon and traveled 14.4 miles from near Taylorville northeastward to Holt.  Some of the heaviest damage was near the intersection of Interstate 59 and McFarland Blvd.  The upper floor of the Scottish Inn was destroyed and a housekeeper at the Inn was killed. Over the entire path of the tornado, 289 homes, 20 businesses, and 21 trailers were destroyed or heavily damaged.  Tornadoes also occurred that day in Calhoun (F0), Cullman (F2), and Walker (F2) counties in Alabama. 

Sources:

Tuscaloosa News (Articles/Photos)
NWS Birmingham
Bill Murray, Alabamawx.com